[Von Recklinghausen's disease associated with pancreatic somatostatinoma].

Abstract

INTRODUCTION:

Pancreatic somatostatinoma is a rare entity and its association with Von Recklinghausen's disease has only been described on two occasions. We report a new observation, with clinical and evolving status differing from those described in isolated cases of somatostatinoma.

OBSERVATION:

A 28 year-old man presenting with familial Von Recklinghausen's disease, had suffered for 10 years from paroxysmic abdominal pain. He was hospitalized for intense pain. Imaging revealed a retroperineal tumoral formation. Following duodenopancreatectomy, somatostatinoma was diagnosed. Diffuse metastatic miliary was revealed and multiple glandular metastases.

DISCUSSION:

Other than the rarity of the morbid association (pancreatic somatostatinoma and Von Recklinghausen's disease) described, this case is particular in that the patient was very young, symptomatology was unapparent and tumoral evolution was minimal.

• Authors: P Thannberger, J M Wilhelm, A Derragui, O Saraceni, P Kieffer
• Journal: Presse medicale (Paris, France : 1983) (Presse Med) Vol. 30 Issue 35 Pg. 1741-3 (Nov 24 2001) ISSN: 0755-4982 [Print] France
• Vernacular Title: Maladie de Von Recklinghausen associée à un somatostatinome pancréatique.
• PMID: 11769067 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Somatostatin

Topics

• Adult
• Humans
• Male
• Neurofibromatosis 1 (complications, diagnosis)
• Pancreas (pathology)
• Pancreatic Neoplasms (complications, diagnosis, pathology, surgery)
• Somatostatin (blood)
• Somatostatinoma (complications, diagnosis, pathology, surgery)