[Acute anterior wall infarct in a 31-year-old patient after administration of methylergometrin for peripartal vaginal hemorrhage].

Abstract

CASE REPORT:

After administration methylergometrine 30 minutes after delivery for peripartal vaginal bleeding a 31-year-old female patient developed an acute anterior wall myocardial infarction. Coronary angiography 7 hours after beginning of the chest pain demonstrated a dissection with a large thrombus in the proximal left anterior descending artery, followed by a complete occlusion in the periphery of the vessel (Figure 1). After applying rtPA intravenously, coronary angiography showed 24 hours later an open vessel without thrombotic material (Figure 2).

CONCLUSION:

Coronary artery spasm induced by methylergometrine must be regarded as the main reason for the dissection and thrombus formation followed by a myocardial infarction.

• Authors: M Ribbing, H Reinecke, G Breithardt, S Kerber
• Journal: Herz (Herz) Vol. 26 Issue 7 Pg. 489-93 (Nov 2001) ISSN: 0340-9937 [Print] Germany
• Vernacular Title: Akuter Vorderwandinfarkt einer 31-jährigen Patientin nach Gabe von Methylergometrin aufgrund peripartaler vaginaler Blutung.
• PMID: 11765484 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Methylergonovine

Topics

• Adult
• Coronary Angiography
• Coronary Thrombosis (chemically induced, diagnosis)
• Coronary Vasospasm (chemically induced, diagnosis)
• Female
• Humans
• Injections, Intramuscular
• Methylergonovine (administration & dosage, adverse effects)
• Myocardial Infarction (chemically induced, diagnosis)
• Postpartum Hemorrhage (drug therapy)
• Risk Factors