[Experimental study of the effectiveness of the use of imunofan in the treatment of viral diseases of the eye].

Abstract

The efficiency of local therapy of ocular inflammations with a new drug immunophane was evaluated in experiments. Ophthalmological and morphological methods were used in the study. Experiments on 30 Wistar rats (60 eyes) demonstrated the absence of toxic effect on intact ocular tissues. Therapeutic efficiency of immunophane was demonstrated in 13 rabbits (26 eyes) with ophthalmic herpes. The advantages of subconjunctival injections of immunophane in comparison with instillations of leukocytic interferon are demonstrated.

• Authors: A V Kordunianu, V N Kushnir, O S Slepova, G G Ziangirova, N V Eshanu, G I Krichevskaia
• Journal: Vestnik oftalmologii (Vestn Oftalmol) 2001 Sep-Oct Vol. 117 Issue 5 Pg. 43-7 ISSN: 0042-465X [Print] Russia (Federation)
• Vernacular Title: Eksperimental'noe issledovanie éffektivnosti primeneniia imunofana pri lechenii virusindutsirovannoĭ patologii glaz.
• PMID: 11765469 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Antiviral Agents
• Interferon-alpha
• Oligopeptides
• thymohexin

Topics

• Adjuvants, Immunologic (administration & dosage, therapeutic use)
• Animals
• Antiviral Agents (administration & dosage, therapeutic use)
• Interferon-alpha (administration & dosage, therapeutic use)
• Keratitis, Herpetic (drug therapy)
• Oligopeptides (administration & dosage, therapeutic use)
• Rabbits
• Rats
• Rats, Wistar
• Time Factors