[Immune and interferon system in patients with bronchial asthma].

We studied the levels of acute inflammation phase proteins (AIPP), production of alpha, gamma and serum interferons, the activity of epsilon-receptors of T-lymphocytes in 39 patients with bronchial asthma (BA). Correlations were made with the process severity and basic therapy. We discovered imbalance of immunoregulatory mechanisms: enhanced AIPP synthesis, low production of induced alpha and gamma interferons, elevated concentrations of poor-differentiated T-lymphocytes. This confirms persisting inflammation in BA.
AuthorsO V Artem'eva, A I Kognovitskaia, T M Iurina, V F Semenkov, L D Serova, N K Chereĭskaia, O N Slivets
JournalKlinicheskaia meditsina (Klin Med (Mosk)) Vol. 79 Issue 10 Pg. 21-3 ( 2001) ISSN: 0023-2149 [Print] Russia
Vernacular TitleSostoianie immunnoĭ i interferonovoĭ sistem u bol'nykh bronkhial'noĭ astmoĭ.
PMID11759400 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Bacterial Proteins
  • Immunoglobulins
  • Interferons
  • Asthma (immunology, metabolism)
  • Bacterial Proteins (metabolism)
  • Humans
  • Immunoglobulins (immunology)
  • Interferons (blood)
  • T-Lymphocytes (immunology)

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