[Immune and interferon system in patients with bronchial asthma].

Abstract

We studied the levels of acute inflammation phase proteins (AIPP), production of alpha, gamma and serum interferons, the activity of epsilon-receptors of T-lymphocytes in 39 patients with bronchial asthma (BA). Correlations were made with the process severity and basic therapy. We discovered imbalance of immunoregulatory mechanisms: enhanced AIPP synthesis, low production of induced alpha and gamma interferons, elevated concentrations of poor-differentiated T-lymphocytes. This confirms persisting inflammation in BA.

• Authors: O V Artem'eva, A I Kognovitskaia, T M Iurina, V F Semenkov, L D Serova, N K Chereĭskaia, O N Slivets
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 79 Issue 10 Pg. 21-3 ( 2001) ISSN: 0023-2149 [Print] Russia (Federation)
• Vernacular Title: Sostoianie immunnoĭ i interferonovoĭ sistem u bol'nykh bronkhial'noĭ astmoĭ.
• PMID: 11759400 (Publication Type: English Abstract, Journal Article)

Chemical References

• Bacterial Proteins
• Immunoglobulins
• Interferons

Topics

• Asthma (immunology, metabolism)
• Bacterial Proteins (metabolism)
• Humans
• Immunoglobulins (immunology)
• Interferons (blood)
• T-Lymphocytes (immunology)