Abstract |
The evidence for the value of noxytiolin (Noxyflex) in peritonitis is contradictory. In a controlled trial of the effect of noxytiolin in pertonitis in rabbits we have found a significant increase in mortality in the trial group compared with a control group, but no significant difference when a dose equivalent to the recommended human dose is used. The postoperative course is adversely affected in the animals receiving noxytiolin.
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Authors | D W King, J F Gurry, B N Brooke |
Journal | The British journal of surgery
(Br J Surg)
Vol. 62
Issue 8
Pg. 645-6
(Aug 1975)
ISSN: 0007-1323 [Print] England |
PMID | 1174808
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Noxythiolin
(administration & dosage, adverse effects, therapeutic use)
- Peritonitis
(drug therapy)
- Rabbits
- Thiourea
(analogs & derivatives)
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