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The effect of noxytiolin in experimental peritonitis.

Abstract
The evidence for the value of noxytiolin (Noxyflex) in peritonitis is contradictory. In a controlled trial of the effect of noxytiolin in pertonitis in rabbits we have found a significant increase in mortality in the trial group compared with a control group, but no significant difference when a dose equivalent to the recommended human dose is used. The postoperative course is adversely affected in the animals receiving noxytiolin.
AuthorsD W King, J F Gurry, B N Brooke
JournalThe British journal of surgery (Br J Surg) Vol. 62 Issue 8 Pg. 645-6 (Aug 1975) ISSN: 0007-1323 [Print] England
PMID1174808 (Publication Type: Journal Article)
Chemical References
  • Noxythiolin
  • Thiourea
Topics
  • Animals
  • Noxythiolin (administration & dosage, adverse effects, therapeutic use)
  • Peritonitis (drug therapy)
  • Rabbits
  • Thiourea (analogs & derivatives)

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