HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Physical condition of preterm infants with periventricular leukomalacia.

Abstract
The aim of this study is to determine the general condition of preterm infants with severe brain lesions and to compare it with that of normal preterm infants. The Score for Neonatal Acute Physiology (SNAP) was calculated in nine preterm infants with periventricular leukomalacia (PVL) whose initial electroencephalograms showed grade IV depression (PVL group), 18 preterm infants who did not require mechanical ventilation during the neonatal period, Spontaneous respiration (SR group), and 18 preterm infants who required mechanical ventilation (MV group). The sum of the following four items in SNAP was separately calculated and called the 'lung score': PaO(2), PaO(2)/FiO(2) ratio, PaCO(2), and oxygenation index. In addition to SNAP, we evaluated some neonatal variables. SNAP is lower in the SR group than in the PVL (P<0.05) or MV (P<0.01) groups. The lung score was also lower in the SR group than in the PVL (P<0.05) or MV (P<0.01) groups. On the other hand, the residual score (SNAP minus lung score) was not significantly different among the three groups. The physical condition of infants with PVL was not poor, although respiratory distress was often observed.
AuthorsA Okumura, F Hayakawa, T Kato, T Kubota, K Maruyama, K Itomi, K Kuno, K Watanabe
JournalBrain & development (Brain Dev) Vol. 23 Issue 8 Pg. 805-9 (Dec 2001) ISSN: 0387-7604 [Print] Netherlands
PMID11720798 (Publication Type: Journal Article)
Chemical References
  • Oxygen
  • Dopamine
Topics
  • Apgar Score
  • Brain (abnormalities, pathology, physiopathology)
  • Dopamine (therapeutic use)
  • Electroencephalography
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature (physiology)
  • Leukomalacia, Periventricular (complications, diagnosis, physiopathology)
  • Oxygen (blood)
  • Respiratory Insufficiency (diagnosis, etiology, physiopathology)
  • Respiratory Physiological Phenomena

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: