[Effect of a new triclosan-containing mouth rinse on oral infection].

Abstract

OBJECTIVE:

To study the effect of a new Triclosan-containing mouthrinse--LIBO Anti-plaque mouth rinse on oral infection.

METHODS:

1. Before and after the use of triclosan mouthrinse: the gingival data were checked and secorded; plaque sausples were collected, cultured in selective and non-selective media, bacteria were isolated, sounted, and compased. 2. With Streptococcus mutans and P. Gingivalis as experimental bacteria, triclosan and chlorhexidine (CHX) mouthrinses anti-bacterium substance, the minimum inhibitory concentrations (MICs) of the two rinses were compared. 3. Smooth plates with the film of Streptococcus mutans C were set in different mouthrinses and water. Observing the exfoliation of bacteria film from the plates in three agents.

RESULTS:

1. Triclosan mouthrinse was effective to decrease the plaque index (PLI) and supragingival bleeding index (SBI). 2. The bacteria count obtained after use of triclosan mouthrinse was lower than that before using it. 3. The minimum inhibitory concentrations of triclosan mouthrinse against Streptococcus mutans C was much lower than that of chlorhexidine mouthrinse. 4. In triclosan mouthrinse, the bacterial films were most easily exfoliated from the plate. Triclosan mouthrinse has strongest anti-adhesion effect among the three tested agents.

CONCLUSIONS:

Triclosan mouthrinse has continuous disinfecting effect and help control the formation and adhesion of dental plaque.

• Authors: X Wu, T Zhang, Y Zhang
• Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology (Zhonghua Kou Qiang Yi Xue Za Zhi) Vol. 36 Issue 4 Pg. 301-3 (Jul 2001) ISSN: 1002-0098 [Print] China
• PMID: 11718017 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Anti-Infective Agents, Local
• Mouthwashes
• Triclosan
• Chlorhexidine

Topics

• Adult
• Aged
• Aged, 80 and over
• Anti-Infective Agents, Local (therapeutic use)
• Chlorhexidine (pharmacology)
• Dental Plaque (drug therapy, microbiology)
• Female
• Humans
• Male
• Microbial Sensitivity Tests
• Middle Aged
• Mouthwashes (chemistry)
• Oral Hygiene
• Streptococcus mutans (drug effects)
• Triclosan (therapeutic use)