[Granulomatous slack skin: partial remission following intralesional administration of interferon-alpha and PUVA].

Abstract

Granulomatous slack skin (GSS) is a rare cutaneous T-cell lymphoma which typically runs a protracted and indolent course. On histopathological assessment lymphoid infiltrates with multinucleated giant cells in the dermis and subcutis with elastophagocytosis can be observed. Skin lesions are characterized by pendulous folds. We report on the successful response of the lesions to intralesional interferon alpha combined with PUVA.

• Authors: T Schmook, G Hofbauer, W Kempf, G Burg, R Dummer
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 52 Issue 10 Pt 2 Pg. 985-8 (Oct 2001) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Granulomatous slack skin. Partielle Remission unter intraläsionärer Gabe von Interferon-alpha und PUVA.
• PMID: 11715400 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents
• Interferon-alpha

Topics

• Adult
• Antineoplastic Agents (administration & dosage)
• Follow-Up Studies
• Humans
• Injections, Intralesional
• Interferon-alpha (administration & dosage)
• Lymphoma, T-Cell, Cutaneous (diagnosis, drug therapy, pathology)
• Male
• PUVA Therapy
• Remission Induction
• Skin (pathology)
• Skin Neoplasms (diagnosis, drug therapy, pathology)
• Time Factors