Abstract |
Gastroesophageal reflux disease is a frequent illness with important implications on quality of life. In order to evaluate in a general population the efficacy and safety of lansoprazole 15 mg in maintenance therapy of reflux oesophagitis in current medical practice, an open label observational study was conducted in Belgium. 1.709 patients were included by 429 general practitioners during 3 to 6 months from 1997 to 1999. At the end of the study, symptoms improved or disappeared in 88% of patients. No drug related severe adverse event was reported. This study confirmed that lansoprazole 15 mg is effective and safe in maintenance treatment of reflux oesophagitis.
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Authors | J Penson, M A Azerad, M Puttemans, C Fassotte |
Journal | Revue medicale de Liege
(Rev Med Liege)
Vol. 56
Issue 9
Pg. 625-9
(Sep 2001)
ISSN: 0370-629X [Print] Belgium |
Vernacular Title | Etude casuistique complémentaire de l'efficacité, la tolérance et la sécurité du lansoprazole 15 mg dans le traitement d'entretien de l'oesophagite de reflux en pratique médicale quotidienne en Belgique (record RU49749/R002). |
PMID | 11702504
(Publication Type: Clinical Trial, English Abstract, Journal Article)
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Chemical References |
- 2-Pyridinylmethylsulfinylbenzimidazoles
- Enzyme Inhibitors
- Lansoprazole
- Omeprazole
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Topics |
- 2-Pyridinylmethylsulfinylbenzimidazoles
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Child
- Enzyme Inhibitors
(adverse effects, pharmacology)
- Esophagitis, Peptic
(drug therapy, pathology)
- Female
- Humans
- Lansoprazole
- Male
- Middle Aged
- Omeprazole
(adverse effects, analogs & derivatives, pharmacology)
- Prospective Studies
- Treatment Outcome
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