[Transeptal steroids in necrotizing scleritis].

Abstract

PURPOSE:

To analyze the efficacy of transeptal corticosteroid injections in necrotizing scleritis as additional treatment to systemic immunosuppressors.

METHOD:

Eleven patients with necrotizing scleritis treated with systemic immunosuppressors received transeptal corticosteroid injections during periods of active inflammation.

RESULTS:

Transeptal corticosteroid injections in addition to systemic immunosuppressors halted active imflammation in 10 of 11 patients with necrotizing scleritis, showing few side effects. Because of that, there was no need to increase dosage nor to switch systemic immunosuppressors. There was no evidence of scleral perforation, scleral thinning and no cases of staphyloma were observed.

CONCLUSIONS:

Systemic immunosuppressors remain as the first choice treatment for necrotizing scleritis; however, transeptal corticosteroid injections may be helpful as additional treatment during periods of active inflammation.

• Authors: M Sainz De La Maza Serra, J Folch Ramos
• Journal: Archivos de la Sociedad Espanola de Oftalmologia (Arch Soc Esp Oftalmol) Vol. 76 Issue 10 Pg. 589-92 (Oct 2001) ISSN: 0365-6691 [Print] Spain
• Vernacular Title: Esteroides transeptales en la escleritis necrotizante.
• PMID: 11685675 (Publication Type: English Abstract, Journal Article)

Chemical References

• Immunosuppressive Agents
• Cyclophosphamide
• Azathioprine
• Prednisone
• Methotrexate

Topics

• Adult
• Aged
• Aged, 80 and over
• Azathioprine (administration & dosage)
• Cyclophosphamide (administration & dosage)
• Female
• Follow-Up Studies
• Humans
• Immunosuppressive Agents (administration & dosage)
• Injections (methods)
• Male
• Methotrexate (administration & dosage)
• Middle Aged
• Prednisone (administration & dosage)
• Scleritis (drug therapy)