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Cheilitis granulomatosa Miescher: treatment with clofazimine and review of the literature.

Abstract
Cheilitis granulomatosa Miescher is a rare condition of unknown cause characterized by intermittent lip swelling that gradually persists and causes cosmetic deformity. We report the case of a young woman with cheilitis granulomatosa as a monosymptomatic manifestation of Melkersson-Rosenthal syndrome successfully treated by the antileprosy agent clofazimine, and propose clofazimine as an alternative treatment in cases refractory to corticosteroids. The differential diagnosis and current methods of treatment are summarized, and the literature is reviewed and discussed.
AuthorsG J Ridder, M Fradis, E Löhle
JournalThe Annals of otology, rhinology, and laryngology (Ann Otol Rhinol Laryngol) Vol. 110 Issue 10 Pg. 964-7 (Oct 2001) ISSN: 0003-4894 [Print] United States
PMID11642431 (Publication Type: Case Reports, Journal Article, Review)
Chemical References
  • Anti-Inflammatory Agents, Non-Steroidal
  • Coloring Agents
  • Clofazimine
Topics
  • Adolescent
  • Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
  • Clofazimine (therapeutic use)
  • Coloring Agents (therapeutic use)
  • Female
  • Humans
  • Melkersson-Rosenthal Syndrome (drug therapy)

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