Retransfusion acidosis after brief haemorrhagic hypotension in the dog.

Abstract

Dogs under chloralose anasthesia were bled at a rate of 50 ml/min to a total of 25 ml/kg body weight and 2 minutes later a quick reinfusion of adequate volumes of blood, dextran, or Locke's solution was done. Within 2 minutes after reinfusion, the pH of arterial blood fell by 0.074--0.127; concurrently, PaCO2 rose by 9.2-12.9 mm Hg. A close correlation was demonstrated between these changes. After retransfusion, PaO2 and the arterial lactic acid level did not change significantly. Thus retransfusion acidosis in the dog appears after a brief hypotensive period, too, but cannot be attributed to a "washout" of lactate from the tissues.

• Authors: L Takács, G Szántó, E Vándor
• Journal: Acta chirurgica Academiae Scientiarum Hungaricae (Acta Chir Acad Sci Hung) Vol. 17 Issue 2 Pg. 161-7 ( 1976) ISSN: 0001-5431 [Print] Hungary
• PMID: 11626 (Publication Type: Journal Article)

Chemical References

• Lactates
• Carbon Dioxide
• Oxygen

Topics

• Acidosis (etiology)
• Animals
• Blood Pressure
• Blood Transfusion, Autologous
• Carbon Dioxide (blood)
• Dogs
• Female
• Hemorrhage (complications)
• Hydrogen-Ion Concentration
• Hypotension (complications)
• Lactates (blood)
• Male
• Oxygen (blood)