Abstract | PURPOSE: METHOD: A prospective study of 21 consecutive eyes (21 patients) was performed. Sufficient antibacterial, antifungal, or antiviral agents were applied to eradicate causative organisms before permanent or temporary amniotic membrane transplantation, or a combination of the two in few patients. The amniotic membrane was soaked in antiinfective agents before transplantation in all cases. RESULTS: After amniotic membrane transplantation, follow-up times ranged from 4 to 28 months (mean, 18 months). Clinical indications included Staphylococcus species (four cases), Pseudomonas species (five cases), Acanthamoeba species (three cases), fungus (two cases), and herpesvirus (seven cases). The corneal surface was healed successfully and recurrences of microbial infection were not noted in any case. Visual acuity was improved in cases that were nonscarring or after additional penetrating keratoplasty. CONCLUSION:
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Authors | J S Kim, J C Kim, T W Hahn, W C Park |
Journal | Cornea
(Cornea)
Vol. 20
Issue 7
Pg. 720-6
(Oct 2001)
ISSN: 0277-3740 [Print] United States |
PMID | 11588424
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Acanthamoeba Keratitis
(parasitology, surgery)
- Adolescent
- Adult
- Aged
- Amnion
(transplantation)
- Corneal Ulcer
(microbiology, parasitology, surgery, virology)
- Eye Infections, Bacterial
(microbiology, surgery)
- Female
- Humans
- Keratitis, Herpetic
(microbiology, surgery)
- Male
- Middle Aged
- Ophthalmologic Surgical Procedures
- Prospective Studies
- Visual Acuity
- Wound Healing
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