| Abstract | A 71-year-old woman showed disorientation 7 days after simple mastectomy for right breast cancer. Computed tomography of the brain was normal. The level of serum sodium was very low (110 mEq/l), while the urine sodium level was normal. The osmolality of urine was higher (342 mosmol/kg) than that of serum (220 mosmol/kg). These data suggested a syndrome of inappropriate secretion of antidiuretic hormone. A fluid restriction, infusion of hypertonic saline and administration of diuretics gradually increased the level of serum sodium. Subsequently, disorientation disappeared. This is a rare case of the syndrome of inappropriate secretion of antidiuretic hormone caused by simple mastectomy, a relatively minor surgical procedure. |
| Authors | H Hashida, T Honda, H Morimoto, T Sasaki, Y Aibara, M Yamanaka
(Affiliation: Department of Internal Medicine, Ehime Prefectural Iyomishima Hospital.)
|
| Journal | Internal medicine (Tokyo, Japan)
(Intern Med)
Vol. 40
Issue 9
Pg. 911-4
(Sep 2001)
ISSN: 0918-2918 Japan |
| PMID | 11579955
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
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| Topics |
- Aged
- Breast Neoplasms
(surgery)
- Diagnosis, Differential
- Female
- Humans
- Inappropriate ADH Syndrome
(blood, diagnosis, etiology)
- Mastectomy, Simple
(adverse effects)
- Osmolar Concentration
- Sodium
(blood)
|
