HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Dermatomyositis and sarcoid-like reaction associated with multiple myeloma treated effectively by high-dose chemotherapy and autologous peripheral blood stem cell transplantation.

Abstract
We report the case of a 46-year-old male who developed dermatomyositis and a sarcoid-like reaction in association with testicular relapse of multiple myeloma. The myositis progressed despite chemotherapy directed at the underlying malignant disorder and immunosuppressive treatment. There was, however, a dramatic and sustained response to high-dose chemotherapy and autologous peripheral blood stem cell transplantation which resulted in resolution of the myopathy and partial resolution of the sarcoid-like reaction. This case report highlights the potential of autologous stem cell transplantation as treatment for para-neoplastic disorders associated with haematological malignancies.
AuthorsR Chakraverty, N Rabin, K Peggs, S Robinson, J R Duncan, K Yong
JournalBone marrow transplantation (Bone Marrow Transplant) Vol. 27 Issue 11 Pg. 1215-7 (Jun 2001) ISSN: 0268-3369 [Print] England
PMID11551034 (Publication Type: Case Reports, Journal Article)
Topics
  • Antineoplastic Combined Chemotherapy Protocols (administration & dosage)
  • Combined Modality Therapy
  • Dermatomyositis (diagnosis, etiology, therapy)
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Male
  • Middle Aged
  • Multiple Myeloma (complications, therapy)
  • Recurrence
  • Sarcoidosis (diagnosis, etiology, therapy)
  • Testicular Neoplasms (therapy)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: