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Calcifying lupus panniculitis in a patient with subacute cutaneous lupus erythematosus: response to diltiazem and chloroquine.

Abstract
Lupus panniculitis has been reported to occur with a frequency of 2-3% in patients with lupus erythematosus (LE). It is most often reported in association with lesions of discoid LE. We describe a patient with subacute cutaneous LE who developed calcified nodules that were histopathologically consistent with lupus panniculitis. She was treated with a combination of chloroquine and diltiazem with a good therapeutic response. The addition of diltiazem may be beneficial in patients with calcified nodules of lupus panniculitis.
AuthorsK W Morgan, J P Callen
JournalThe Journal of rheumatology (J Rheumatol) Vol. 28 Issue 9 Pg. 2129-32 (Sep 2001) ISSN: 0315-162X [Print] Canada
PMID11550987 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Chloroquine
  • Diltiazem
Topics
  • Adult
  • Biopsy, Needle
  • Calcinosis (complications, drug therapy, pathology)
  • Chloroquine (administration & dosage)
  • Diltiazem (administration & dosage)
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • Humans
  • Lupus Erythematosus, Cutaneous (complications, drug therapy, pathology)
  • Panniculitis, Lupus Erythematosus (complications, drug therapy, pathology)
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome

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