Retinal degeneration under the effect of antibodies to recoverin.

Abstract	Serious changes in the retina, diagnosed as retinal degeneration and uveitis, are observed only in the presence of high titers of antibodies to recoverin (Ca2+-binding protein, a paraneoplastic antigen) in the blood of rabbits. Negligible changes in the retina of rabbits with low antibody titers are detected only by cytohistochemical analysis of the retina. No changes in the retina develop in rabbits intravenously injected with antibodies to recoverin.
Authors	A V Bazhin, O S Slepova, N K Tikhomirova
Journal	Bulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 131 Issue 4 Pg. 350-2 (Apr 2001) ISSN: 0007-4888 [Print] United States
PMID	11550024 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Antibodies, Neoplasm Antigens, Neoplasm Calcium-Binding Proteins Eye Proteins Lipoproteins Nerve Tissue Proteins Recoverin Hippocalcin
Topics	Animals Antibodies, Neoplasm (immunology) Antigens, Neoplasm (immunology) Calcium-Binding Proteins (immunology) Eye Proteins Hippocalcin Lipoproteins Nerve Tissue Proteins Rabbits Recoverin Retina (immunology, pathology) Retinal Degeneration (immunology, pathology)

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