[Indium-111-oxine labeled platelet and leucocyte scintigraphy for diagnosis of thrombi and inflammation].

Abstract

There were many studies for diagnosis of localization and activity of thrombi and inflammation using indium-111-oxine labeled platelet (In-plt) and leucocyte scintigraphy (In-WBC), respectively. The study using these techniques is decreasing recently, because other diagnostic modarities have been developed and the techniques of these scintigraphy are complicated. However, because these scintigraphy are noninvasive, it is expected that these are widely applied to the clinical diagnosis and follow up. 1. Platelet scintigraphy can visualized thrombi and distinguish the activation of platelet aggregation. There were many reports and reviews. I reviewed recent studies in cardiovascular diseases and our cases. 2. Leucocyte scintigraphy (In-WBC) is usually used for the detection of inflammation. Furthermore, it is possible that In-WBC can detect inflammation of the arteriosclerotic lesion of the aortic wall. I introduced our studies of In-WBC in aortic aneurysma and aortic dissection. The In-WBC maybe useful for detection of inflammation of the aortic aneurysma and evaluation of prognosis of aortic dissection.

• Authors: M Ohyanagi
• Journal: Kaku igaku. The Japanese journal of nuclear medicine (Kaku Igaku) Vol. 38 Issue 4 Pg. 295-300 (Jul 2001) ISSN: 0022-7854 [Print] Japan
• PMID: 11530375 (Publication Type: Journal Article, Review)

Chemical References

• Organometallic Compounds
• Radiopharmaceuticals
• indium oxine
• Oxyquinoline

Topics

• Aortic Dissection (diagnostic imaging)
• Aortic Aneurysm (diagnostic imaging)
• Blood Platelets
• Cardiovascular Diseases (diagnostic imaging)
• Humans
• Inflammation (diagnostic imaging)
• Leukocytes
• Organometallic Compounds
• Oxyquinoline (analogs & derivatives)
• Radionuclide Imaging
• Radiopharmaceuticals
• Thrombosis (diagnostic imaging)