KCB-328 (C&C Research Labs).

Abstract

C & C Research Labs is investigating the class III antiarrhythmic KCB-328 as a potential treatment for heart arrhythmia [310688]. The compound is potent in vitro, with little reverse frequency-dependence when compared with E-4031 (qv) and dofetilide (qv) [223384]. KCB-328 is in preclinical development [351687].

• Authors: G Billman
• Journal: Current opinion in investigational drugs (London, England : 2000) (Curr Opin Investig Drugs) Vol. 2 Issue 1 Pg. 93-6 (Jan 2001) ISSN: 1472-4472 [Print] England
• PMID: 11527019 (Publication Type: Journal Article)

Chemical References

• 1-(2-amino-4-methanesulfonamidophenoxy)-2-(N-(3,4-dimethoxyphenethyl)-N-methylamino)ethane
• Anti-Arrhythmia Agents
• Phenethylamines
• Sulfonamides

Topics

• Animals
• Anti-Arrhythmia Agents (pharmacology)
• Humans
• Phenethylamines (pharmacology)
• Sulfonamides (pharmacology)