Chiron has developed and launched Menjugate, a
vaccine for the treatment for meningococcus C
infections caused by the pathogen Neisseria meningitidis [177064]. In August 1999,
Chiron filed with the UK MCA for a license to market Menjugate. The licence was granted in March 2000 [339082], [344773], [357897] and as of April 2000, a vaccination program was underway in the UK [362152]. Menjugate is indicated for children of 12 months and older, but
Chiron was expecting approval in the US for infants younger than 12 months by the end of 2000. The company will also pursue mutual recognition in Europe [376204]. In August 2000,
Chiron received marketing clearance for Menjugate from the Irish Medicines Board as a conjugate against meningococcal C disease [378353]. The
vaccine employs CRM-conjugate technology, whereby a
diphtheria toxoid is used as a
carrier protein for the
meningitis C-specific
antigens. The
vaccine is being developed for its potential to provide protection against
meningitis in both adults and infants. In July 2000,
Chiron entered into a comarketing and co-promotion agreement with Aventis Pasteur under which Aventis will assist
Chiron in marketing and sales efforts for Menjugate in the UK [374760].