Mechanism of action of anti-influenza benzamidine derivatives.

Abstract

Benzamidine derivatives exhibited a high antiviral effect in vivo against influenza virus strains A2/Adachi and B/Lee. The inhibiting properties of anti-influenza benzamidine derivatives on the virus-induced inflammation undoubtedly plays an important role in the clarification of the mechanism of action of these drugs.

• Authors: H Fujita, Y Seto, S Toyoshima
• Journal: Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 7 Issue 4 Pg. 426-30 (Apr 1975) ISSN: 0066-4804 [Print] United States
• PMID: 1147578 (Publication Type: Journal Article)

Chemical References

• Amidines
• Anti-Inflammatory Agents
• Antiviral Agents
• Benzamidines

Topics

• Amidines (pharmacology)
• Animals
• Anti-Inflammatory Agents (pharmacology)
• Antiviral Agents (pharmacology, therapeutic use)
• Benzamidines (pharmacology, therapeutic use)
• Chick Embryo
• Male
• Mice
• Orthomyxoviridae (drug effects)
• Orthomyxoviridae Infections (drug therapy)
• Rats
• Virus Replication (drug effects)