Transitional cell carcinoma of the urinary bladder following exposure to cyclophosphamide in childhood.

Abstract

With the increasing survival of children with malignancies, the long-term effects of chemotherapies are now becoming important and one of these dreadful long-term complications is the development of a second malignancy. Described here is a case of transitional cell carcinoma of the bladder developing 8 years following exposure to cyclophosphamide for the treatment of embryonal rhabdomyosarcoma.

• Authors: S Agarwala, A K Hemal, A Seth, A K Gupta, V Bhatnagar, D K Mitra
• Journal: European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie (Eur J Pediatr Surg) Vol. 11 Issue 3 Pg. 207-10 (Jun 2001) ISSN: 0939-7248 [Print] United States
• PMID: 11475121 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dactinomycin
• Vincristine
• Cyclophosphamide

Topics

• Adolescent
• Antineoplastic Combined Chemotherapy Protocols
• Bone Neoplasms (congenital, drug therapy)
• Carcinoma, Transitional Cell (chemically induced, diagnostic imaging, therapy)
• Combined Modality Therapy
• Cyclophosphamide (adverse effects, therapeutic use)
• Cystoscopy (methods)
• Dactinomycin
• Follow-Up Studies
• Humans
• Male
• Monitoring, Physiologic
• Radiography
• Radiotherapy, Adjuvant
• Rhabdomyosarcoma (congenital, drug therapy)
• Time Factors
• Treatment Outcome
• Urinary Bladder Neoplasms (chemically induced, diagnostic imaging, therapy)
• Vincristine