Synthesis of a non-natural T-antigen containing glycosphingolipid.

Abstract	A non natural glycosphingolipid containing the mucin derived, cancer associated disaccharide moiety Galbeta1-->3GalNAc, the T-antigen, alpha linked to a ceramide, has been synthesised via the protected disaccharide glycosyl trichloroacetimidate. The product has potential as a cancer vaccine.
Authors	L Cipolla, M Meldal
Journal	Carbohydrate letters (Carbohydr Lett) Vol. 4 Issue 1 Pg. 29-34 ( 2000) ISSN: 1073-5070 [Print] Switzerland
PMID	11469335 (Publication Type: Journal Article)
Chemical References	Antigens, Tumor-Associated, Carbohydrate Cancer Vaccines Glycosphingolipids Thomsen-Friedenreich antigen
Topics	Antigens, Tumor-Associated, Carbohydrate (chemistry, immunology) Cancer Vaccines (chemical synthesis, chemistry) Glycosphingolipids (chemical synthesis, chemistry, immunology) Humans Magnetic Resonance Spectroscopy Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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