Abstract |
A prophylactic approach to the management of postoperative pain is described: ketoprofen, a nonsteroid antiinflammatory drug, was used, which possesses numerous advantages and a variety of dosage forms. To cancer patients subjected to extensive radical operations on the pelvic organs, head, and neck, ketonal ( ketoprofen) was injected intramuscularly or rectally in a dose of 100 mg 1 h before surgery and in a daily dose of 300 mg during the postoperative period. Adequate postoperative monoanalgesia with ketonal was attained in 47% patients. In the rest patients ketonal was combined with medium-potent opioid tramadol. A more potent opioid buprenorfin (sangesik) in the minimal daily dose of 0.3 mg was required in only 2 cases. Nonsteroid antiinflammatory drug ketoprofen (ketonal) in therapeutic doses administered preventively before surgery intramuscularly or rectally notably decreased the acuity of the postoperative pain syndrome.
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Authors | N A Osipova, V A Beresnev, M S Vetsheva, T V Dolgopolova |
Journal | Anesteziologiia i reanimatologiia
(Anesteziol Reanimatol)
1999 Nov-Dec
Issue 6
Pg. 71-4
ISSN: 0201-7563 [Print] Russia (Federation) |
Vernacular Title | Ketoprofen (ketonal)--sredstvo profilaktiki i lecheniia posleoperatsionnoĭ boli. |
PMID | 11452775
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Analgesics, Opioid
- Anti-Inflammatory Agents, Non-Steroidal
- Tramadol
- Buprenorphine
- Ketoprofen
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Topics |
- Administration, Rectal
- Adolescent
- Adult
- Aged
- Analgesics, Opioid
(administration & dosage, therapeutic use)
- Anti-Inflammatory Agents, Non-Steroidal
(administration & dosage, therapeutic use)
- Buprenorphine
(administration & dosage, therapeutic use)
- Drug Therapy, Combination
- Female
- Humans
- Injections, Intramuscular
- Ketoprofen
(administration & dosage, therapeutic use)
- Male
- Middle Aged
- Neoplasms
(surgery)
- Pain, Postoperative
(drug therapy, prevention & control)
- Postoperative Care
- Preoperative Care
- Time Factors
- Tramadol
(administration & dosage, therapeutic use)
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