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Persistent pigmented purpuric eruption associated with mycosis fungoides: a case report and review of the literature.

Abstract
A purpuric eruption may be an unusual early manifestation of mycosis fungoides (MF). On the other hand, persistent pigmented purpuric dermatoses (PPPD) may, occasionally, evolve to cutaneous T-cell lymphoma. Coexistence of these two conditions has been reported, but it is extremely rare. We present the case of an elderly woman with a long-standing pruritic, pigmented purpuric eruption. On 1-year follow-up, histological features suggesting early MF were observed and molecular analysis of the rearrangement of T-cell receptor genes revealed clonality. Our patient may represent a case of PPPD evolving to MF, a case of MF clinically featuring PPPD, or an intermediate condition in a nosological continuity extending from PPPD to MF. A persistent pigmented purpuric eruption may rarely be a harbinger of cutaneous T-cell lymphoma. Therefore, vigilant long-term follow-up of PPPD is highly recommended.
AuthorsS Georgala, A C Katoulis, S Symeonidou, C Georgala, G Vayopoulos
JournalJournal of the European Academy of Dermatology and Venereology : JEADV (J Eur Acad Dermatol Venereol) Vol. 15 Issue 1 Pg. 62-4 (Jan 2001) ISSN: 0926-9959 [Print] England
PMID11451328 (Publication Type: Case Reports, Journal Article, Review)
Topics
  • Female
  • Humans
  • Middle Aged
  • Mycosis Fungoides (complications, pathology)
  • Purpura (complications, pathology)
  • Skin Neoplasms (complications, pathology)

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