Abstract |
A purpuric eruption may be an unusual early manifestation of mycosis fungoides (MF). On the other hand, persistent pigmented purpuric dermatoses (PPPD) may, occasionally, evolve to cutaneous T-cell lymphoma. Coexistence of these two conditions has been reported, but it is extremely rare. We present the case of an elderly woman with a long-standing pruritic, pigmented purpuric eruption. On 1-year follow-up, histological features suggesting early MF were observed and molecular analysis of the rearrangement of T-cell receptor genes revealed clonality. Our patient may represent a case of PPPD evolving to MF, a case of MF clinically featuring PPPD, or an intermediate condition in a nosological continuity extending from PPPD to MF. A persistent pigmented purpuric eruption may rarely be a harbinger of cutaneous T-cell lymphoma. Therefore, vigilant long-term follow-up of PPPD is highly recommended.
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Authors | S Georgala, A C Katoulis, S Symeonidou, C Georgala, G Vayopoulos |
Journal | Journal of the European Academy of Dermatology and Venereology : JEADV
(J Eur Acad Dermatol Venereol)
Vol. 15
Issue 1
Pg. 62-4
(Jan 2001)
ISSN: 0926-9959 [Print] England |
PMID | 11451328
(Publication Type: Case Reports, Journal Article, Review)
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Topics |
- Female
- Humans
- Middle Aged
- Mycosis Fungoides
(complications, pathology)
- Purpura
(complications, pathology)
- Skin Neoplasms
(complications, pathology)
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