[Controlled clinical trial of parsalmide in patients with predominantly neuro-anxiety syndromes. Comparison with chlordiazepoxide].

Abstract

The anxiolytic and tranquillizing effect of a new compound called parsalmide was studied in a group of 20 patients suffering from medium anxiety neurosis. The new drug also possesses anti-inflammatory and analgesic effects. The technique employed was the double blind, between patients, crossover system and chlordiazepoxide was used for comparison purposes. Parsalmide proved to possess an anxiolytic-tranquillizing action comparable to that of chlordiazepoxide and, unlike the latter, was quite free from unpleasant side effects, such as somnolence and asthenia.

• Authors: V Poli
• Journal: Minerva medica (Minerva Med) Vol. 67 Issue 52 Pg. 3409-12 (Oct 31 1976) ISSN: 0026-4806 [Print] Italy
• Vernacular Title: Sperimentazione clinica controllata di parsalmide in pazienti con sindromi prevalentemente neuro-ansiose. Confronto con il clordiazepossido
• PMID: 11424 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Anti-Anxiety Agents
• Anti-Inflammatory Agents, Non-Steroidal
• Benzamides
• Chlordiazepoxide

Topics

• Adult
• Aged
• Anti-Anxiety Agents
• Anti-Inflammatory Agents, Non-Steroidal (adverse effects, therapeutic use)
• Anxiety Disorders (drug therapy)
• Benzamides (adverse effects, therapeutic use)
• Chlordiazepoxide (therapeutic use)
• Clinical Trials as Topic
• Drug Evaluation
• Female
• Humans
• Male
• Middle Aged