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Allergic granulomatosis secondary to a limited form of Churg-Strauss syndrome.

Abstract
Allergic granulomatosis is a disorder of obscure etiology characterized by infiltration of lymph nodes with histiocytic granulomas and eosinophils. In this report, we describe a case of allergic granulomatosis that is consistent with Churg-Strauss disease limited to lymph nodes. The histologic findings of this patient's lymph nodes demonstrated eosinophilic abscesses and ring-shaped necrotizing and nonnecrotizing granulomas surrounding hyperplastic germinal centers. We report herein a rare type of reactive lymphadenopathy and present its histologic, immunohistochemical, and flow cytometric findings, which may allow its distinction from other lymphadenopathies.
AuthorsH Cualing, L Schroder, C Perme
JournalArchives of pathology & laboratory medicine (Arch Pathol Lab Med) Vol. 125 Issue 7 Pg. 954-7 (Jul 2001) ISSN: 0003-9985 [Print] United States
PMID11419986 (Publication Type: Case Reports, Journal Article)
Topics
  • Churg-Strauss Syndrome (immunology, pathology)
  • Diagnosis, Differential
  • Flow Cytometry
  • Humans
  • Immunohistochemistry
  • Immunophenotyping
  • Lymph Nodes (immunology, pathology)
  • Male
  • Middle Aged

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