The in vivo activity of olamufloxacin (HSR-903) in systemic and urinary tract infections in mice.

Abstract	The in vivo activity of olamufloxacin (HSR-903), a new fluoroquinolone, was evaluated and compared with ciprofloxacin, sparfloxacin and levofloxacin. Olamufloxacin was active against systemic infection in mice inoculated with both Gram-positive and -negative bacteria. Olamufloxacin had equal efficacy for experimental urinary tract infections in mice caused by Pseudomonas aeruginosa.
Authors	S Yoshizumi, Y Takahashi, M Murata, H Domon, N Furuya, Y Ishii, T Matsumoto, A Ohno, K Tateda, S Miyazaki, K Yamaguchi
Journal	The Journal of antimicrobial chemotherapy (J Antimicrob Chemother) Vol. 48 Issue 1 Pg. 137-40 (Jul 2001) ISSN: 0305-7453 [Print] England
PMID	11418525 (Publication Type: Journal Article)
Chemical References	Anti-Infective Agents Fluoroquinolones Quinolones olamufloxacin
Topics	Animals Anti-Infective Agents (therapeutic use) Bacterial Infections (drug therapy) Fluoroquinolones Male Mice Mice, Inbred ICR Quinolones (therapeutic use) Urinary Tract Infections (drug therapy)

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