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Delay of natural bone loss by higher intakes of specific minerals and vitamins.

Abstract
For early prevention or inhibition of postmenopausal and age-related bone loss, nutritional interventions might be a first choice. For some vitamins and minerals an important role in bone metabolism is known or suggested. Calcium and vitamin D support bone mineral density and are basic components in most preventive strategies. Magnesium is involved in a number of activities supporting bone strength, preservation, and remodeling. Fluorine and strontium have bone-forming effects. However, high amounts of both elements may reduce bone strength. Boron is especially effective in case of vitamin D, magnesium, and potassium deficiency. Vitamin K is essential for the activation of osteocalcin. Vitamin C is an important stimulus for osteoblast-derived proteins. Increasing the recommended amounts (US RDA 1989), adequate intakes (US DRI 1997), or assumed normal intakes of mentioned food components may lead to a considerable reduction or even prevention of bone loss, especially in late postmenopausal women and the elderly.
AuthorsA Schaafsma, P J de Vries, W H Saris
JournalCritical reviews in food science and nutrition (Crit Rev Food Sci Nutr) Vol. 41 Issue 4 Pg. 225-49 (May 2001) ISSN: 1040-8398 [Print] United States
PMID11401244 (Publication Type: Journal Article, Review)
Chemical References
  • Minerals
  • Vitamins
  • Vitamin K
  • Vitamin D
  • Magnesium
  • Boron
  • Ascorbic Acid
  • Calcium
  • Strontium
Topics
  • Ascorbic Acid (therapeutic use)
  • Bone Density (drug effects)
  • Boron (therapeutic use)
  • Calcium (therapeutic use)
  • Female
  • Humans
  • Magnesium (therapeutic use)
  • Middle Aged
  • Minerals (therapeutic use)
  • Osteoporosis (diet therapy, prevention & control)
  • Osteoporosis, Postmenopausal (prevention & control)
  • Strontium (therapeutic use)
  • Vitamin D (therapeutic use)
  • Vitamin K (therapeutic use)
  • Vitamins (therapeutic use)

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