Abstract |
For early prevention or inhibition of postmenopausal and age-related bone loss, nutritional interventions might be a first choice. For some vitamins and minerals an important role in bone metabolism is known or suggested. Calcium and vitamin D support bone mineral density and are basic components in most preventive strategies. Magnesium is involved in a number of activities supporting bone strength, preservation, and remodeling. Fluorine and strontium have bone-forming effects. However, high amounts of both elements may reduce bone strength. Boron is especially effective in case of vitamin D, magnesium, and potassium deficiency. Vitamin K is essential for the activation of osteocalcin. Vitamin C is an important stimulus for osteoblast-derived proteins. Increasing the recommended amounts (US RDA 1989), adequate intakes (US DRI 1997), or assumed normal intakes of mentioned food components may lead to a considerable reduction or even prevention of bone loss, especially in late postmenopausal women and the elderly.
|
Authors | A Schaafsma, P J de Vries, W H Saris |
Journal | Critical reviews in food science and nutrition
(Crit Rev Food Sci Nutr)
Vol. 41
Issue 4
Pg. 225-49
(May 2001)
ISSN: 1040-8398 [Print] United States |
PMID | 11401244
(Publication Type: Journal Article, Review)
|
Chemical References |
- Minerals
- Vitamins
- Vitamin K
- Vitamin D
- Magnesium
- Boron
- Ascorbic Acid
- Calcium
- Strontium
|
Topics |
- Ascorbic Acid
(therapeutic use)
- Bone Density
(drug effects)
- Boron
(therapeutic use)
- Calcium
(therapeutic use)
- Female
- Humans
- Magnesium
(therapeutic use)
- Middle Aged
- Minerals
(therapeutic use)
- Osteoporosis
(diet therapy, prevention & control)
- Osteoporosis, Postmenopausal
(prevention & control)
- Strontium
(therapeutic use)
- Vitamin D
(therapeutic use)
- Vitamin K
(therapeutic use)
- Vitamins
(therapeutic use)
|