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Clonidine treatment increases tics in patients with Tourette syndrome: case report.

Abstract
Clonidine usually serves as a tic-suppressing agent in patients with Tourette syndrome. A case study is presented in which clonidine at subclinical concentrations led to an exacerbation of the tics and caused severe systemic heat sensations. Involvement of functional abnormalities of the hypothalamus in Tourette syndrome is hypothesized.
AuthorsA R Kessler
JournalJournal of child neurology (J Child Neurol) Vol. 16 Issue 5 Pg. 380-1 (May 2001) ISSN: 0883-0738 [Print] United States
PMID11392527 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Adrenergic alpha-Agonists
  • Clonidine
Topics
  • Adrenergic alpha-Agonists (administration & dosage, adverse effects)
  • Child
  • Clonidine (administration & dosage, adverse effects)
  • Humans
  • Male
  • Tics (chemically induced, diagnosis)
  • Tourette Syndrome (drug therapy)

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