Curdlan sulfate induces the downmodulation of chemokine receptors leading to suppression of HIV infection.

• Authors: T Naito, M Okada, H Ogasawara, H Kaneko, T Hishikawa, T Matsumoto, I Sekigawa, H Hashimoto, Y Kaneko
• Journal: Journal of acquired immune deficiency syndromes (1999) (J Acquir Immune Defic Syndr) Vol. 26 Issue 5 Pg. 512-3 (Apr 15 2001) ISSN: 1525-4135 [Print] United States
• PMID: 11391175 (Publication Type: Letter)

Chemical References

• Anti-HIV Agents
• Glucans
• Receptors, CCR5
• beta-Glucans
• curdlan sulfate

Topics

• Anti-HIV Agents (pharmacology)
• Down-Regulation
• Glucans (pharmacology)
• HIV Infections (drug therapy, virology)
• HIV-1 (drug effects, metabolism)
• Humans
• Leukocytes, Mononuclear (drug effects, metabolism, virology)
• Receptors, CCR5 (drug effects, metabolism)
• beta-Glucans