[Effect of acute congestive splenomegaly on erythropoiesis in rats].

Abstract

Spleen veins ligature (SVL) led to acute congestive splenomegaly in rats with subsequent normochromic anaemia disappearing on the 21st day after the SVL. An appreciable depression of the bone marrow erythropoiesis, particularly of the so called "proliferating erythroblastic islets" number, was evident on the 7th and 14th days of post-SVL period. The post-SVL anaemia was also associated with occurrence of the "islets" missing central macrophages and eosinophil-enriched "islets" in bone marrow.

• Authors: I A Tishevskoĭ, Iu M Zakharov, N V Tishevskaia
• Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova (Ross Fiziol Zh Im I M Sechenova) Vol. 87 Issue 3 Pg. 353-9 (Mar 2001) ISSN: 0869-8139 [Print] Russia (Federation)
• Vernacular Title: Vliianie ostroĭ zastoĭnoĭ splenomegalii na sostoianie éritrona u krys.
• PMID: 11386159 (Publication Type: English Abstract, Journal Article)

Topics

• Acute Disease
• Animals
• Bone Marrow Cells (cytology)
• Erythroblasts (pathology)
• Erythropoiesis
• Female
• Ligation
• Rats
• Spleen (blood supply)
• Splenomegaly (blood)