Increased plasma neurotensin concentrations in patients with Parkinson's disease.

Abstract

Plasma neurotensin (NT) was measured by radioimmunoassay in propanol extracted and unextracted plasma from 16 parkinsonian patients (four before treatment) and 16 age and sex matched controls. Mean plasma NT concentrations were consistently higher in parkinsonian patients than in controls and higher in the four untreated patients than in levodopa treated patients suggesting that plasma NT measurement may represent an easy detectable additional index in diagnosing parkinsonism and provides a novel approach to research in this field.

• Authors: R M Schimpff, C Avard, G Fénelon, A M Lhiaubet, L Tennezé, M Vidailhet, W Rostène
• Journal: Journal of neurology, neurosurgery, and psychiatry (J Neurol Neurosurg Psychiatry) Vol. 70 Issue 6 Pg. 784-6 (Jun 2001) ISSN: 0022-3050 [Print] England
• PMID: 11385014 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Neurotensin

Topics

• Aged
• Chromatography, Liquid (methods)
• Female
• Humans
• Male
• Middle Aged
• Neurotensin (blood)
• Parkinson Disease (blood)