Pharmacologic management of the patient with type 2 diabetes.

Abstract

The United Kingdom Prospective Diabetes Study (UKPDS) demonstrated that the benefit of optimal glucose control in type 2 diabetes is a significant reduction in diabetes-related complications. In addition, the UKPDS also demonstrated that type 2 diabetes is a progressive disorder. Whereas many patients may initially receive good glucose control from a single medication, they are likely to require multiple medications to maintain this same level of glucose control as the disease progresses. The recent introduction of several new classes of glucose-lowering medications has allowed health care providers to explore the use of these medications alone and in combination to help patients with type 2 diabetes maintain optimal glucose control. Therefore, it is important to understand the physiologic actions, benefits, and risks of these medications in the treatment of type 2 diabetes.

• Authors: L Quinn
• Journal: The Nursing clinics of North America (Nurs Clin North Am) Vol. 36 Issue 2 Pg. 217-42, vi (Jun 2001) ISSN: 0029-6465 [Print] United States
• PMID: 11382561 (Publication Type: Journal Article, Review)

Chemical References

• Blood Glucose
• Hypoglycemic Agents

Topics

• Blood Glucose (analysis, drug effects)
• Combined Modality Therapy
• Diabetes Mellitus, Type 2 (complications, drug therapy, metabolism, physiopathology)
• Disease Progression
• Drug Interactions
• Humans
• Hypoglycemic Agents (classification, metabolism, pharmacology, therapeutic use)
• Insulin Resistance
• Patient Selection
• Treatment Outcome