Abstract | BACKGROUND:
Intralesional injection of corticosteroids is an effective treatment for tumors of the head and neck. Complications are rare but include permanent loss of vision. We designed a study to investigate the mechanism for this complication. METHODS: RESULTS: A total of 71 injections (range, 8-33 injections per patient) was performed. The total volume of corticosteroid ranged from 0.9 to 2.1 mL. In 63 of 71 injections, the maximum pressure exceeded 100 mm Hg (range, 18.65-842.18 mm Hg). Each surgeon produced injection pressures greater than the systemic arterial pressures of each patient. CONCLUSIONS:
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Authors | J E Egbert, S Paul, W K Engel, C G Summers |
Journal | Archives of ophthalmology (Chicago, Ill. : 1960)
(Arch Ophthalmol)
Vol. 119
Issue 5
Pg. 677-83
(May 2001)
ISSN: 0003-9950 [Print] United States |
PMID | 11346395
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Glucocorticoids
- Triamcinolone
- betamethasone acetate phosphate
- betamethasone sodium phosphate
- Betamethasone
- triamcinolone diacetate
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Topics |
- Betamethasone
(administration & dosage, adverse effects, analogs & derivatives)
- Blood Pressure
- Embolism
(etiology)
- Eye
(blood supply)
- Eyelid Neoplasms
(drug therapy, pathology)
- Female
- Glucocorticoids
(administration & dosage, adverse effects)
- Hemangioma, Capillary
(drug therapy, pathology)
- Humans
- Infant
- Injections, Intralesional
- Male
- Orbital Neoplasms
(drug therapy, pathology)
- Postoperative Complications
- Pressure
(adverse effects)
- Triamcinolone
(administration & dosage, adverse effects, analogs & derivatives)
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