Fibrin glue for all anal fistulas.

Abstract

The aim of this study was to determine if a new sphincter muscle-sparing technique that uses fibrin glue was effective in closing all types of anal fistulas. All patients with anal fistulas who were seen by a single surgeon over a 2-year period were treated with fibrin glue. Six to 8 weeks after a seton was placed in the fistula tract, either autologous fibrin glue or commercially available fibrin sealant was used to close the fistula tract. Twenty patients were treated with a mean follow-up of 10 months. Etiology of the anal fistulas was as follows: cryptoglandular in 13, Crohn's disease in four, and miscellaneous in three. Fibrin glue closure of the anal fistula was successful initially in 15 patients (75%) and was successful after a second treatment in two additional patients, for an overall fibrin glue fistula closure rate of 85% (17 of 20). Functional results have remained excellent with no patient reporting any change in continence after treatment. Fibrin glue is simple and effective treatment for all anal fistulas with excellent functional results.

• Authors: S M Sentovich
• Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (J Gastrointest Surg) 2001 Mar-Apr Vol. 5 Issue 2 Pg. 158-61 ISSN: 1091-255X [Print] United States
• PMID: 11331478 (Publication Type: Journal Article)

Chemical References

• Fibrin Tissue Adhesive
• Tissue Adhesives

Topics

• Adult
• Aged
• Female
• Fibrin Tissue Adhesive (therapeutic use)
• Humans
• Male
• Middle Aged
• Rectal Fistula (surgery)
• Tissue Adhesives (therapeutic use)
• Treatment Outcome