Allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate (IPBC) - an update.

Abstract

Results from 3 1/2 years of routine patch testing with 3-iodo-2-propynyl-butylcarbamate (IPBC) are presented. From 1996 to 1999, a total of 3168 persons (2093 women and 1075 men) were patch tested with IPBC, and 7 cases were found to be positive. In 2 cases, sensitization could be attributed to cosmetics, and in a further 2 cases cosmetics were the most likely cause of sensitisation. It is concluded that the use of IPBC in cosmetic products can lead to contact sensitization and allergic contact dermatitis. 2 of the 7 reported cases with IPBC allergy were also found positive to thiuram, and possible cross-reactivity between IPBC and thiuram is discussed.

• Authors: L E Bryld, T Agner, T Menné
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 44 Issue 5 Pg. 276-8 (May 2001) ISSN: 0105-1873 [Print] England
• PMID: 11298692 (Publication Type: Journal Article)

Chemical References

• Allergens
• Carbamates
• Cosmetics
• Preservatives, Pharmaceutical
• Thiram
• 3-iodo-2-propynylbutylcarbamate

Topics

• Allergens (adverse effects)
• Carbamates (adverse effects)
• Cosmetics (adverse effects)
• Cross Reactions
• Dermatitis, Allergic Contact (diagnosis, etiology)
• Female
• Humans
• Male
• Patch Tests
• Preservatives, Pharmaceutical (adverse effects)
• Thiram (adverse effects)