Abstract | BACKGROUND: METHODS: RESULTS: We demonstrate a high incidence of the disease in a cohort of patients affected by overt and non-overt diabetes mellitus (T1DM and T2DM) as well as in obese subjects and a correlation between this disorder and hypertryglyceridemia (T1DM, obese-T2DM and obese patients), hypo-HDL-cholesterolemia (obese-T2DM, non-obese-T2DM and obese patients) and hyper- LDL-cholesterolemia (obese patients). In obese-T2DM patients, as well as in obese patients, we observed 40% of DISH, in non obese-T2DM patients the presence of DISH was 30%, while in T1DM patients and impaired glucose tolerance 26.6% and 22.2, respectively. However, a correlation between DISH and the relative hyperinsulinemia in obese patients during an oral glucose tolerance test is not documented. CONCLUSIONS: Our study confirms the prevalence of DISH in diabetes mellitus and obesity, the association with an impaired lipidic profile and the low percentage of symptomatic patients.
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Authors | S Coaccioli, G Fatati, L Di Cato, D Marioli, E Patucchi, C Pizzuti, M Ponteggia, A Puxeddu |
Journal | Panminerva medica
(Panminerva Med)
Vol. 42
Issue 4
Pg. 247-51
(Dec 2000)
ISSN: 0031-0808 [Print] Italy |
PMID | 11294086
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Blood Glucose
(metabolism)
- Diabetes Complications
- Diabetes Mellitus
(metabolism)
- Female
- Humans
- Hyperostosis, Diffuse Idiopathic Skeletal
(etiology)
- Lipids
(blood)
- Male
- Middle Aged
- Obesity
(complications, metabolism)
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