Cellular angiofibroma of the vulva with DNA ploidy analysis.

Abstract

Cellular angiofibroma (CAF) is a recently described rare soft tissue neoplasm of the vulva (with only four reported cases) that typically occurs as a well-circumscribed solid rubbery vulvar mass in middle-aged women. The distinct histologic features of bland spindle cells admixed with numerous hyalinized medium to small blood vessels, and a vimentin-positive desmin-negative immunoprofile differentiates this neoplasm from other vulvar tumors such as angiomyofibroblastoma and aggressive angiomyxoma. In this report an additional case of CAF is presented with DNA ploidy analysis and CD99 immunohistochemistry.

• Authors: J L Curry, J L Olejnik, E M Wojcik
• Journal: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists (Int J Gynecol Pathol) Vol. 20 Issue 2 Pg. 200-3 (Apr 2001) ISSN: 0277-1691 [Print] United States
• PMID: 11293169 (Publication Type: Case Reports, Journal Article)

Chemical References

• 12E7 Antigen
• Antigens, CD
• CD99 protein, human
• Cell Adhesion Molecules
• DNA, Neoplasm
• Vimentin

Topics

• 12E7 Antigen
• Adult
• Angiofibroma (diagnosis, genetics, surgery)
• Antigens, CD (analysis)
• Cell Adhesion Molecules (analysis)
• DNA, Neoplasm (analysis)
• Female
• Humans
• Ploidies
• Vimentin (analysis)
• Vulvar Neoplasms (diagnosis, genetics, surgery)