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Improvement in right lung atelectasis (middle lobe syndrome) following administration of low-dose roxithromycin.

Abstract
Middle lobe syndrome is a distinct clinical entity characterized by right middle lobe atelectasis. Prompt diagnosis and initiation of medical therapy including the administration of antibiotics and the avoidance of irritating agents may be effective. However, abnormal shadows on chest radiography remain unchanged even when acute symptoms have disappeared, suggesting latent lesional inflammation or recurrence. We describe 2 cases of atelectasis in the middle lobe of the right lung which resolved completely after administration of low-dose roxithromycin. Thus, low-dose therapy with a macrolide could be of interest or some value in these cases, but it is too early to draw a definite conclusion.
AuthorsM Kawamura, Y Arai, M Tani
JournalRespiration; international review of thoracic diseases (Respiration) Vol. 68 Issue 2 Pg. 210-4 ( 2001) ISSN: 0025-7931 [Print] Switzerland
PMID11287839 (Publication Type: Journal Article)
CopyrightCopyright 2001 S. Karger AG, Basel
Chemical References
  • Anti-Bacterial Agents
  • Roxithromycin
Topics
  • Aged
  • Anti-Bacterial Agents (administration & dosage)
  • Female
  • Humans
  • Middle Lobe Syndrome (diagnostic imaging, drug therapy)
  • Pregnancy
  • Roxithromycin (administration & dosage)
  • Tomography, X-Ray Computed

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