Studies on marine microorganisms. IV. A new antibiotic SS-228 Y produced by Chainia isolated from shallow sea mud.

Abstract

A new antibiotic named SS-228 Y, which inhibits growth of Gram-positive bacteria, Ehrlich carcinoma in mice, and dopamine-beta-hydroxylase, was obtained from a species of Chainia isolated from shallow sea mud in Sagami Bay. It was yellowish brown powder having the molecular formula C19H1406. From the physical and chemical properties, SS-228 Y was concluded to b a new antibiotic having structure of peri-hydroxyquinone moiety.

• Authors: T Okazaki, T Kitahara, Y Okami
• Journal: The Journal of antibiotics (J Antibiot (Tokyo)) Vol. 28 Issue 3 Pg. 176-84 (Mar 1975) ISSN: 0021-8820 [Print] England
• PMID: 1126873 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Antibiotics, Antineoplastic
• Culture Media
• Soil

Topics

• Actinomycetales (metabolism)
• Animals
• Anti-Bacterial Agents (biosynthesis, isolation & purification, pharmacology)
• Antibiotics, Antineoplastic (analysis)
• Carcinoma, Ehrlich Tumor (drug therapy)
• Cell Wall (analysis)
• Chemical Phenomena
• Chemistry, Physical
• Culture Media
• Mice
• Seawater
• Soil (analysis)
• Spectrophotometry, Infrared
• Spectrophotometry, Ultraviolet
• Staphylococcus (drug effects)