[Peridural fibrosis in lumbar disc surgery--pathogenesis, clinical problems and prophylactic attempts].

Abstract

Postoperative peridural fibrosis is unavoidable adverse effect of lumbar disc surgery. This process is disadvantageous both to the patient and to the surgeon. It is assumed that peridural fibrosis is responsible for as much as 25% of all Failed Back Surgery Syndrome. In case of reherniated discs requiring reoperation epidural scar may cause technical difficulties. Thus the prevention or inhibition of postoperative peridural fibrosis and adhesions is an essential goal for successful lower back surgery. The authors review new opinions on pathophysiology of peridural fibrosis, clinical aspects of the process, results of experimental approaches for limiting peridural fibrosis and perspective of anti-adhesion gel Adcon-L.

• Authors: P Gasiński, M Radek, J Jóźwiak, P Łyczak
• Journal: Neurologia i neurochirurgia polska (Neurol Neurochir Pol) 2000 Sep-Oct Vol. 34 Issue 5 Pg. 983-93 ISSN: 0028-3843 [Print] Poland
• Vernacular Title: Blizna oponowa w operacjach odcinka ledźwiowego kregosłupa--mechanizm powstawania, problemy kliniczne i próby profilaktyki.
• PMID: 11253486 (Publication Type: English Abstract, Journal Article, Review)

Topics

• Fibrosis
• Humans
• Intervertebral Disc Displacement (pathology, surgery)
• Low Back Pain (etiology)
• Lumbar Vertebrae (pathology, surgery)
• Postoperative Complications (prevention & control)
• Reoperation
• Tissue Adhesions (complications)
• Treatment Failure