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Absorbable versus nonabsorbable membranes and bone grafts in the treatment of ligature-induced peri-implantitis defects in dogs. Part I. A clinical investigation.

Abstract
The purpose of this study was to clinically evaluate an absorbable collagen membrane (Bio-Gide) and a nonabsorbable polytetrafluoroethylene membrane (PTFE), associated or not with bone grafts, for the treatment of ligature-induced peri-implantitis defects in dogs. The bilateral mandibular premolars were removed from 5 2-year-old mongrel dogs. After 3 months of healing, 3 titanium implants were placed on each side of the mandible. Experimental peri-implantitis was induced after abutment connection. Ligatures and abutments were removed after 1 month and the bone defects were randomly assigned to one of the following treatments: DB: debridement alone; GBR+BG-I: debridement plus PTFE membrane associated with mineralized bone graft (Bio-Oss); GBR+BG-II: debridement plus collagen membrane (Bio-Gide) associated with mineralized bone graft; GBR-I: debridement plus PTFE membrane; GBR-II: debridement plus collagen membrane; BG: debridement plus mineralized bone graft. The peri-implant bone defects were measured before and 5 months after treatment. Results showed the greatest percentage of vertical bone fill for GBR+BG-II (27.77+/-14.07) followed by GBR-II (21.78+/-16.19), BG (21.26+/-6.87), GBR+BG-I (19.57+/-13.36), GBR-I (18.86+/-10.63) and DB (14.03+/-5.6). However, the values were not statistically significant (ANOVA, contrast F test, P=0.612). Within the limits of the present investigation, it can be concluded that no difference was detected among treatments.
AuthorsF H Nociti Jr, M A Machado, C M Stefani, E A Sallum, A W Sallum
JournalClinical oral implants research (Clin Oral Implants Res) Vol. 12 Issue 2 Pg. 115-20 (Apr 2001) ISSN: 0905-7161 [Print] Denmark
PMID11251660 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Bio-Gide
  • Bio-Oss
  • Biocompatible Materials
  • Bone Substitutes
  • Dental Implants
  • Membranes, Artificial
  • Minerals
  • Polytetrafluoroethylene
  • Collagen
Topics
  • Absorbable Implants
  • Alveolar Bone Loss (surgery)
  • Analysis of Variance
  • Animals
  • Biocompatible Materials
  • Bone Regeneration
  • Bone Substitutes
  • Bone Transplantation
  • Collagen
  • Dental Implantation, Endosseous (adverse effects)
  • Dental Implants (adverse effects)
  • Dogs
  • Guided Tissue Regeneration, Periodontal (methods)
  • Implants, Experimental (adverse effects)
  • Ligation
  • Membranes, Artificial
  • Minerals
  • Periodontitis (etiology, surgery)
  • Polytetrafluoroethylene
  • Random Allocation

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