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Frosted branch angiitis in a child with HIV infection.

AbstractPURPOSE:
In adults with human immunodeficiency virus (HIV) infection, frosted branch angiitis is commonly associated with cytomegalovirus retinitis and responds to anti-cytomegalovirus therapy. We describe the first pediatric case of HIV-associated frosted branch angiitis.
METHODS:
Case report.
RESULTS:
A 7-year-old HIV-infected male with frosted branch angiitis was refractory to induction doses of intravenous ganciclovir and foscarnet over a 2-month period. Although cytomegalovirus antigenemia resolved, the angiitis only improved after subsequent treatment with systemic corticosteroids.
CONCLUSION:
Frosted branch angiitis in this patient was not attributed to cytomegalovirus. The pathogenesis of HIV-associated frosted branch angiitis may differ between children and adults.
AuthorsH F Fine, J A Smith, B L Murante, R B Nussenblatt, M R Robinson
JournalAmerican journal of ophthalmology (Am J Ophthalmol) Vol. 131 Issue 3 Pg. 394-6 (Mar 2001) ISSN: 0002-9394 [Print] United States
PMID11239884 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antiviral Agents
  • Glucocorticoids
  • Foscarnet
  • Ganciclovir
Topics
  • Antiviral Agents (therapeutic use)
  • Child
  • Cytomegalovirus Retinitis (complications, diagnosis, drug therapy)
  • Foscarnet (therapeutic use)
  • Ganciclovir (therapeutic use)
  • Glucocorticoids (therapeutic use)
  • HIV Infections (complications, diagnosis, drug therapy)
  • Humans
  • Male
  • Retinal Diseases (diagnosis, drug therapy, etiology)
  • Retinal Vessels (drug effects, pathology)
  • Vasculitis (diagnosis, drug therapy, etiology)

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