Abstract | BACKGROUND: METHODS: Records of patients undergoing intestinal transplantation for desmoid tumors at 2 transplant centers were reviewed for patient age, sex, type of graft, procedure date, tumor site, desmoid complications, medications, extracolonic manifestations, status at follow-up, and length of survival. RESULTS: Nine patients with FAP and intestinal failure caused by desmoid tumors were treated with isolated intestinal (n = 6), multivisceral (n = 2), or combined liver-intestinal transplantation (n = 1). Desmoid tumors recurred in the abdominal walls of 2 patients. Two patients died: one as a result of sepsis, the other because of a rupture of a mycotic aneurysm of the aortic anastomosis. One graft lost to severe rejection was replaced with a second intestinal graft. Eleven to 53 months after transplantation, 7 patients were alive, well, independent of parenteral treatment, and leading apparently normal lifestyles. CONCLUSIONS:
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Authors | M A Chatzipetrou, A G Tzakis, A D Pinna, T Kato, E P Misiakos, A K Tsaroucha, D Weppler, P Ruiz, M Berho, T Fishbein, H O Conn, C Ricordi |
Journal | Surgery
(Surgery)
Vol. 129
Issue 3
Pg. 277-81
(Mar 2001)
ISSN: 0039-6060 [Print] United States |
PMID | 11231455
(Publication Type: Journal Article)
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Topics |
- Adenomatous Polyposis Coli
(complications)
- Adult
- Female
- Fibroma
(etiology, mortality, surgery)
- Graft Rejection
(surgery)
- Humans
- Intestines
(transplantation)
- Liver Transplantation
- Male
- Middle Aged
- Reoperation
- Survival Analysis
- Viscera
(transplantation)
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