Markedly elevated levels of vascular endothelial growth factor, fibroblast growth factor, and interleukin 6 in Meigs syndrome.

Abstract

Analysis of serum and peritoneal and pleural fluid from a patient with Meigs' syndrome revealed high levels of vascular endothelial growth factor, fibroblast growth factor, and interleukin 6. Serum levels declined after removal of the ovarian tumor, along with resolution of ascites and hydrothorax. These findings suggest the involvement of these vasoactive factors in ascites and pleural fluid formation in Meigs' syndrome.

• Authors: Y Abramov, S O Anteby, S J Fasouliotis, V Barak
• Journal: American journal of obstetrics and gynecology (Am J Obstet Gynecol) Vol. 184 Issue 3 Pg. 354-5 (Feb 2001) ISSN: 0002-9378 [Print] United States
• PMID: 11228486 (Publication Type: Case Reports, Journal Article)

Chemical References

• Endothelial Growth Factors
• Interleukin-6
• Lymphokines
• Vascular Endothelial Growth Factor A
• Vascular Endothelial Growth Factors
• Fibroblast Growth Factors

Topics

• Ascites (metabolism)
• Ascitic Fluid (metabolism)
• Endothelial Growth Factors (blood, metabolism)
• Female
• Fibroblast Growth Factors (blood, metabolism)
• Histocytochemistry
• Humans
• Hysterectomy
• Immunoenzyme Techniques
• Interleukin-6 (blood, metabolism)
• Lymphokines (blood, metabolism)
• Meigs Syndrome (blood, metabolism, surgery)
• Middle Aged
• Pleural Effusion, Malignant (metabolism)
• Vascular Endothelial Growth Factor A
• Vascular Endothelial Growth Factors