FR191512, a novel anti-influenza agent isolated from a fungus strain No.17415. I. Taxonomy, fermentation, isolation, physico-chemical properties and structure elucidation.

Abstract

In the course of our screening for anti-influenza agents of microbial origin, FR191512 was isolated from the cultured broth of fungus strain No. 17415 as colorless powder. The structure of FR191512 was determined by several spectroscopic experiments as a novel polyphenolic compound. This compound showed potent antiviral activity against influenza A virus.

• Authors: Y Nishihara, E Tsujii, S Takase, Y Tsurumi, T Kino, M Hino, M Yamashita, S Hashimoto
• Journal: The Journal of antibiotics (J Antibiot (Tokyo)) Vol. 53 Issue 12 Pg. 1333-40 (Dec 2000) ISSN: 0021-8820 [Print] England
• PMID: 11217797 (Publication Type: Journal Article)

Chemical References

• Antiviral Agents
• FR 191512
• Polyesters
• Resorcinols

Topics

• Antiviral Agents (chemistry, isolation & purification, pharmacology)
• Fungi (chemistry)
• Magnetic Resonance Spectroscopy
• Microbial Sensitivity Tests
• Molecular Structure
• Orthomyxoviridae (drug effects)
• Polyesters (chemistry, isolation & purification, pharmacology)
• Resorcinols (chemistry, isolation & purification, pharmacology)
• Spectrometry, Mass, Fast Atom Bombardment