Abstract |
10-Hydroxystearic acid seems to be widely distributed in nature: Bacteria generate it by hydroxylation of oleic acid, but it was found also as constituent of plants, in cancer cell cultures and in mammalian tissue homogenates. Investigation of 10-hydroxystearic acid, obtained from mammalian tissue homogenates, revealed its identity with that of bacteria. Thus not 10-hydroxystearic acid is widely distributed in nature but its producers: bacteria. When biological material is processed in aqueous media, lipases are activated, these cleave membrane phospholipids. Thus liberated oleic acid is the substrate for widespread bacteria which are introduced into the media when the work up procedure is done in not sterile surrounding. The bacteria transform then oleic acid to 10R-hydroxystearic acid.
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Authors | P Adam, K Hannemann, J Reiner, G Spiteller |
Journal | Zeitschrift fur Naturforschung. C, Journal of biosciences
(Z Naturforsch C J Biosci)
2000 Nov-Dec
Vol. 55
Issue 11-12
Pg. 965-70
ISSN: 0939-5075 [Print] Germany |
PMID | 11204203
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Membrane Lipids
- Phospholipids
- Stearic Acids
- Oleic Acid
- 10-hydroxystearic acid
- Lipase
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Topics |
- Animals
- Bacteria
(metabolism)
- Gas Chromatography-Mass Spectrometry
- Lipase
(metabolism)
- Liver
(metabolism)
- Magnetic Resonance Spectroscopy
- Membrane Lipids
(metabolism)
- Oleic Acid
(metabolism)
- Phospholipids
(metabolism)
- Stearic Acids
(analysis, chemistry, metabolism)
- Swine
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