Abstract |
30 patients of 23-73 years old with endogenic and reactive depressions were treated with fevarin. The clinical state of the patients was estimated by means of Hamilton Depression Rating Scale (Ham-D). Fevarin was administrated in daily dose of 100-300 mg; the course of the treatment was equal to 4-8 weeks. The anxiolytic and antidepressive effects of fevarin were developed from the 5-7 days of the therapy: an anxiety disappeared completely by the end of the 3-d week. The most pronounced antidepressive effect was found for the classic depression with melancholy. A mild simulative effect and a normalization of a sleep were also observed. An improvement of the mental state was found in the all the patients by the end of the treatment: in 60% it was significant (a complete remission); in 40%--a considerable improvement was observed with the reduction of all clinical components of the depressive state. Fluvoxamine was found to be the high effective preparation for both endogenic and reactive depressions.
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Authors | M S Sheĭfer, M I Tsybina, M V Davydenko |
Journal | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
(Zh Nevrol Psikhiatr Im S S Korsakova)
Vol. 100
Issue 12
Pg. 64-7
( 2000)
ISSN: 1997-7298 [Print] Russia (Federation) |
Vernacular Title | Fluvoksamin (fevarin) v terapii depressii. |
PMID | 11195542
(Publication Type: Clinical Trial, English Abstract, Journal Article)
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Chemical References |
- Antidepressive Agents, Second-Generation
- Fluvoxamine
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Topics |
- Adult
- Aged
- Antidepressive Agents, Second-Generation
(administration & dosage, therapeutic use)
- Depressive Disorder
(diagnosis, drug therapy)
- Drug Administration Schedule
- Female
- Fluvoxamine
(administration & dosage, therapeutic use)
- Humans
- Male
- Middle Aged
- Severity of Illness Index
- Treatment Outcome
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