[Extramedullary hematopoiesis as differential mediastinal space-occupying lesion diagnosis].

Abstract

Intrathoracic extramedullary hematopoiesis is a rare disease in the differential diagnosis of mediastinal masses. It is suggested that asymptomatic masses should not be treated. A correct diagnosis can thus help to avoid an operation. The aim of this case report is to draw attention to this phenomenon as a cause of mediastinal masses and to provide information about diagnostic facilities available. We report the case of a 53-year-old male patient with hereditary spherocytosis as well as the case of a 59-year-old male patient with pyruvate kinase deficiency who showed intrathoracic paravertebral masses, that were identified in the first case by video-assisted thoracoscopic intervention (VATS) and in the second case by thoracotomy as a region of extramedullary hematopoiesis.

• Authors: C Roder, H Dienemann
• Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen (Chirurg) Vol. 71 Issue 12 Pg. 1509-12 (Dec 2000) ISSN: 0009-4722 [Print] Germany
• Vernacular Title: Die extramedulläre Blutbildung als Differentialdiagnose der mediastinalen Raumforderung.
• PMID: 11195073 (Publication Type: English Abstract, Journal Article)

Chemical References

• Pyruvate Kinase

Topics

• Diagnosis, Differential
• Hematopoiesis, Extramedullary (physiology)
• Humans
• Male
• Mediastinal Neoplasms (diagnosis, pathology, surgery)
• Middle Aged
• Pyruvate Kinase (deficiency)
• Spherocytosis, Hereditary (diagnosis)
• Thoracic Surgery, Video-Assisted
• Thoracoscopy